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Labcorp pathology offers a comprehensive menu of assays and services to aid in the diagnosis, prognosis, and monitoring of dermatological conditions. In addition, Labcorp pathology’s advanced immunohistochemistry staining techniques allow for tissue conservation on small samples.
Labcorp pathology’s dermatopathologists are subspecialty trained and further accomplished through extensive practical exposure.
Daily review ensures accurate diagnoses. More than one dermatopathologist reviews melanomas and difficult cases, providing a built-in second opinion.
Labcorp pathology maintains relationships with nationally recognized leaders in dermatopathology and utilizes these professionals to review challenging cases.
Labcorp pathology validates and applies the newest laboratory methods and technologies in the delivery of accurate and definitive diagnoses.
Labcorp pathology offers a melanoma FISH panel that can help dermatopathologists diagnose ambiguous skin lesions. This FISH panel consists of RREB1 (6p25), MYB (6q23), 6 centromere, and CCND1 (11q13) and can be useful in differentiating melanomas from benign nevi. The test is available as a stand-alone or can be ordered as a reflex test for lesions deemed ambiguous or suspicious for melanoma by our dermatopathologists.
In patients with malignant melanoma, a mutation in the BRAF gene has been found to significantly improve response rates to therapy using vemurafenib (Zelboraf®*). Labcorp pathology offers a BRAF mutation test that is approved by the FDA as a companion diagnostic.
*Zelboraf is a registered trademark of Genentech, Inc.
Labcorp pathology offers an extensive list of immunohistochemistry including: